Fourth Avenue (the section between downtown and the U of A, that is) has so many murals that I'm always spotting something new. This mural has been at 526 N. 4th for a while, I guess — the store opened and closed before I caught this early-morning photo:
(Update: By October, the mural was gone. You can read more here.)
Update (January 15, 2015): BreakOut Studios has a new mural on the north side of their new location.