Many murals contain a lot of objects. This one is simple: just a zebra on a boarded-up window. What a zebra, though!
I found this on May 11 at the southeast corner of 5th Avenue and 6th Street.
Update (November 23, 2019): When I walked by this mural two weeks ago, it was almost completely gone. A Google Street View vehicle found the same view shown above during April, 2019, so it hasn't been gone long.